AbsorptionIn Biotechnology, absorption is the removal of a particular molecule from a sample by accumulation into a bound water volume which might be present in a densly fibrous material.
In pharmacology (ph
http://en.wikipedia.org/wiki/Absorption_(pharmacok...
Accelerated Stability TestsAccelerated Stability Tests are used to predict the long-term usability of a biotechnology product. A study may require that a product is stored under 'stress' conditions (i.e. a high temperature and
http://biopharminternational.findpharma.com/biopha...
Acceptance Criteria / TestingNumerical limits, ranges or other suitable measures for the acceptance of the results of analytical procedures which a pharmaceutical compound, substance, drug, or (raw) material needs to meet at vari
http://en.wikipedia.org/wiki/Acceptance_testing
Acetonitrile (ACN)Acetonitrile or ACN is s chemical compound. As a sovent ACN is frequently used in High Performance Liquid Chromatography (HPLC)
http://en.wikipedia.org/wiki/Acetonitrile
Acidic VariantAlso know as Charge Variant.
A product that exibits a more negatice charge character than the primary biotherapeutic compound.
http://www.springerlink.com/content/p6427g6580638t...
Active Starting MaterialThe raw or base material that is identified as directly related to the active chemical compound comprising the product, and is defined as the first stage during chemical synthesis at which part one or
http://pharmtech.findpharma.com/pharmtech/Regulato...
AdsorptionA process in which molecules in solution or suspension adhere to cells other than molecules - or to solid serfaces, such as chromatography media. Also: the collection of a substance onto the surface o
http://en.wikipedia.org/wiki/Adsorption
Adventitious agentsAcquired, accidental contaminants in a cell line such as viruses and toxins — often infectious agents.
http://www.cdc.gov/ncidod/eid/vol7no3_supp/krause....
AffinityAffinity comes from the Latin verb affinis = connected with. In pharmacology, biotechnology and chemistry affinity refers to the attaction between particles or substances; relatively speaking, a measu
http://en.wikipedia.org/wiki/Affinity
Affinity chromatographyAffinity chromatography is a chromatographic method that makes use of the specific binding of one molecule to another. It can be used in a number of applications, including nucleic acid purification,
http://en.wikipedia.org/wiki/Affinity_chromatograp...
Affinity tag / Affinity tailAn affinity tag or affinity tail is an amino acid sequence added to a protein to facilitate purification by affinity chromatography. Affinity tags are appended to proteins so that they can be purified
http://mcl1.ncifcrf.gov/waugh_pubs/7_Waugh.pdf
AgaroseAgarose is a polysaccharide (sugar) gelatinous substance obtained from seaweed and used as a solidifying agent (agar)in a microbial culture. It is also used in gel electrophoresis. Historically it is
http://en.wikipedia.org/wiki/Agarose
AggregateA cluster or clustered mass. In biochemical sciences this refers to, for example, a cluster of protein molecules. Aggregates of cells (solid, fluffy, or pelletrized), can clog the pores of filters or
http://dictionary.reference.com/browse/aggregate
Alanine (Ala or A)Alanine (abbreviated as Ala or A) an α-amino acid. There are more than 20 naturally occurring amino acids. Amino acids are molecules containing an amine group, a carboxylic acid group and a side cha
http://en.wikipedia.org/wiki/Alanine
AlbuminsAlbumins are the major plasma protein, responsible for much of the plasma colloidal osmotic pressure and serving as a transport protein for large organic anions (e.g., fatty acids, bilirubin, some dru
http://encyclopedia.farlex.com/Albumins
AlkylationAlkylation is the introduction by substitution, adition or transfer of an alkyl group from into an organic compound. The alkyl group may be transferred as an alkyl carbocation, a free radical, a carba
http://en.wikipedia.org/wiki/Alkylation
Alpha helix (a-helix)A coil or spiral element, the secondary structure of proteins, the alpha helix (α-helix) is a right- or left-handed coiled conformation.
http://en.wikipedia.org/wiki/Alpha_helix
Amino acid analysisAmino acid analysis is the hydrolysis of a protein or peptide into the individual residues (free amino acids), followed by cgromatographic seperation and UV-visible detection for analysis. Amino acid
http://www.informaworld.com/smpp/6084613-47117568/...
Amino AcidsAmino Acids are a class of more than 20 naturally occuring hydrocarbon molecules containing an amine group, a carboxylic acid group and a side chain that varies between different amino acids. These mo
http://en.wikipedia.org/wiki/Amino_acid
AmorphousHaving no definite or apparent shpae, form order; non-crystalline.
http://www.merriam-webster.com/dictionary/Amorphou...
AmpholyteAmpholytes are molecules that contain both acidic and basic groups (and are therefore amphoteric) and will exist mostly as zwitterions in a certain range of pH. The pH at which the average charge is z
http://en.wikipedia.org/wiki/Zwitterion
AmphotericA substance that has both acid and base properties and is capable of functioning either as an acid or as a base. Amphoteric molecules can accept or donate protons to act as an acid or a base.
http://dictionary.reference.com/browse/amphoteric
AmpuleAn ampule (also ampoule or ampulla) is a small, sterile vial with an airtight seal which is used to contain and preserve a single drug dose, usually a solid or liquid. Ampules are commonly made of gl
http://en.wikipedia.org/wiki/Ampoule
AmyloidAn amyloid is an insoluble fibrous protein aggregate sharing specific structural traits. Abnormal accumulation of amyloid in organs may lead to amyloidosis and may play a role in a number of neurodege
http://en.wikipedia.org/wiki/Amyloid
AnaerobicAnaerobic means without air, opposed to aerobic. In biochemistry, it refers to growing in the absence of air or oxigen. Some anaerobic organisms are killed by brief exposure to oxygen, whereas it may
http://en.wikipedia.org/wiki/Anaerobic